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Salix (Furosemide)

Salix (Furosemide) by Merck Animal Health

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What is Salix?
Salix is a diuretic, which is a medication used in many species to remove excess fluid from the body.

Who is it for?
Salix is for dogs, cats, and horses.

What are the benefits?

  • Used to treat congestive heart failure and some other heart diseases
  • Treats fluid in the lungs and certain kidney diseases
  • Also treats high blood pressure, high potassium blood levels, fluid in the abdomen, and certain kinds of tissue swelling

How does Salix work?
Salix works by increasing the amount of salt and water that the kidneys remove from the blood. This extra salt and water is then passed out through the urine.

How is it given?
Salix is given orally, with or without food, with plenty of fresh drinking water. It should only be given to the pet for which it was prescribed. Always follow the dosage instructions provided by your veterinarian. Dosage, frequency, and duration of treatment vary with each disease, disease severity, and response to treatment. If you have difficulty giving the medication, contact your veterinarian immediately.

What results can I expect?
Salix will not cure a disease, but will help manage the symptoms. Salix will start to have an effect within hours of being taken. The effect is short-lived, however, and the drug must consistently be given according to your veterinarian's directions to have the full effect.

What form(s) does it come in?
This medication comes in tablet form.
 

Furosemide
(Lasix, Salix, Disal)

Common Drug Name
Furosemide

Common Brand Names
Lasix, Salix, Disal
Generic products are available.

Storage
Store at room temperature in a tight, light resistant, childproof container.

Uses
Furosemide is a diuretic used in many species to remove excess fluid from the body. Used to treat congestive heart failure, some other heart diseases, pulmonary edema (fluid in the lungs), certain kidney diseases, high blood pressure, high potassium level in the blood, ascites (fluid in the abdomen), and certain kinds of tissue edema (swelling).

Dose and Administration
Always follow the dosage instructions provided by your veterinarian. Dosage, frequency, and duration of treatment vary with each disease, disease severity, and response to treatment. If you have difficulty giving the medication, contact your veterinarian.
May be given with or without food.
If using the transdermal gel, apply to the skin as directed by your veterinarian.
If you miss a dose, give it as soon as you remember.  If it is almost time for the next dose, skip the one you missed and go back to the regular schedule.  Do not give 2 doses at once.
This medication should only be given to the pet for whom it was prescribed.

Possible Side Effects
May include dehydration with excessive thirst and increased or decreased urine production; or electrolyte imbalances (e.g., low sodium, potassium, or calcium), often with rapid heart rate, weakness, depression, vomiting, and restlessness. If you see any of these signs, contact your veterinarian immediately.
Less commonly may see an increase in blood glucose (sugar) level; anemia, resulting in pale gums, tiredness, or weakness; a decrease in white blood cells, making the animal more susceptible to infections; and stomach or intestinal disorders, with vomiting or diarrhea. 
Cats: May affect hearing or balance, or cause a tilt of the head.
Consult your veterinarian if you notice any of the above side effects.
Animals who eat and drink normally are less likely to experience side effects.
If your pet experiences an allergic reaction to the medication, signs may include facial swelling, hives, scratching, sudden onset of diarrhea, vomiting, shock, seizures, pale gums, cold limbs, or coma. If you observe any of these signs, contact your veterinarian immediately.

Precautions
Not for use in animals who are hyper­sensitive (allergic) to it or sulfa drugs (furosemide is chemically similar to some sulfa drugs).
Furosemide will cause your pet to urinate more often. Your pet may have more “accidents” and need to go outside or use the litter box more. Use with caution in animals with kidney disease and diabetes mellitus.
Do not use in animals with anuria (inability to produce urine), progressive kidney disease, electrolyte imbalances, water loss (dehydration), liver disease, diabetes mellitus, vomiting, or diarrhea.
Do not use in pregnant or lactating animals (female animals nursing their young).
Your pet needs to eat and drink well while taking furosemide or the risk of side effects increases. Contact your veterinarian, if your pet is not eating or drinking well.
Consult with your veterinarian regarding the physical examinations and laboratory testing necessary prior to and during treatment with furosemide.

Human Precautions
People with hypersensitivities (allergies) to sulfa drugs should not handle furosemide, or wear gloves and use extreme caution if they do, since allergic reactions could occur just from contact.

Drug, Food, and Test Interactions
Consult your veterinarian before using furosemide with any other medications, including vitamins and supplements, corticosteroids (prednisone, prednisolone,methylprednisolone), amphotericin B, insulin, probenecid, sulfinpyrazone,gentamicin, other aminoslycoside antibiotics, digoxin, enalapril, theophylline, or NSAIDs such as aspirin, deracoxib (Deramaxx), etodolac (EtoGesic), meloxicam (Metacam), carprofen (Novox or Rimadyl), firocoxib (Previcox), tepoxalin (Zubrin), since interactions may occur.

Signs of Toxicity/Overdose
May include hearing loss, electrolyte imbalances, dehydration, lethargy, coma, seizures, heart failure/collapse, and kidney damage, with increased thirst and urination.
If you know or suspect your pet has had an overdose, or if you observe any of these signs in your pet, contact your veterinarian immediately.
Keep this and all other medications out of the reach of children and pets.

This information may not cover all possible uses, directions, side effects, precautions, allergic reactions, drug interactions, or withdrawal times.  Always consult your own veterinarian for specific advice concerning the treatment of your pet.


 

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