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Brand Name
Tylan

Common Drug Name
Tylosin

What is Tylan?
Tylan is an antibiotic used for colitis and chronic diarrhea. Tylan may also decrease the symptoms by affecting the immune system in the intestine.

Who is it for?
May be recommended for off-label use in dogs and cats.

What are the benefits?

• Treats certain types of chronic diarrhea and colitis
• Also affects the intestine's immune system
• Powder form is easy to give with food

How does Tylan work?
Tylan is an antibiotic in the macrolide class that works by inhibiting protein synthesis in certain types of bacteria.

Is there a generic equivalent available?
No.

How is it given?
Tylan powder is given orally with food. Always follow the dosage instructions provided by your veterinarian.

This medication should only be given to the pet for whom it was prescribed.

What results can I expect?
Tylan will not cure the disease, but may help manage the symptoms. It may take a number of days to see an effect. May need to give for a number of weeks, depending upon the specific disease.

What form(s) does it come in?
Tylan comes in powder form.
 

What should I discuss with my veterinarian while considering Tylan?
Be sure to understand the dosing schedule that is prescribed by your veterinarian. Also, discuss what type of effects you can expect to see. Talk about what other treatments may be used in conjunction with Tylan.

Notify your veterinarian of any other medications or supplements your pet is taking, and also if your pet has had any reactions to previous medications.

What should I do if I miss a dose?
If you miss a dose, give it as soon as you remember. If it is almost time for the next dose, skip the one you missed and go back to the regular schedule. Do not give two doses at once.

What is the most important information I should know?
Colitis and chronic diarrhea can be very difficult to treat. Tylan may help manage the symptoms but will not generally cure the disease. Understand how to properly dose this powdered medication.

Who should not take it?
Not for use in animals hypersensitive (allergic) to tylosin, erythromycin, or other antibiotics in the macrolide class. The safety of Tylan in pregnant or lactating animals (female animals nursing their young) is not known.

Do not use in horses.

What side effects may be seen when taking Tylan?
Some animals may have vomiting and a slight worsening of the diarrhea at the beginning of treatment. Consult your veterinarian if you notice any of these side effects.

If your pet experiences an allergic reaction to the medication, signs may include facial swelling, hives, scratching, sudden onset of diarrhea, vomiting, shock, seizures, pale gums, cold limbs, or coma. If you observe any of these signs, contact your veterinarian immediately.

How is it stored?
Store at room temperature in a tight, light-resistant, childproof container. Keep out of reach of children and pets.

What should I do if I know of or suspect there has been an overdose?
Toxicity is very rare. If you know or suspect your pet has had an overdose, contact your veterinarian immediately.

What should I avoid when giving my pet Tylan?
Consult your veterinarian before using this medication with other medications, including vitamins and supplements, digoxin, methylprednisolone, warfarin, or theophylline, since interactions may occur.
 

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Tylosin
(Tylan)

Common Drug Name
Tylosin

Common Brand Names
Tylan
No oral generic products are available.

Storage
Store at room temperature in a tight, light resistant, childproof container.

Uses
Tylosin is an antibiotic in the macrolide class. It is used to treat certain types of chronic diarrhea or Mycoplasma infections in cats, dogs, birds, reptiles, and other species.

Dose and Administration
Always follow the dosage instructions provided by your veterinarian.
When giving orally, give with food.
Tylosin powder is bitter. If you have difficulty giving the medication, contact your veterinarian. Your veterinarian may have the pharmacist put the powder in capsules, which may be easier to give.
If you mix the tylosin with water before giving it to your pet, it must be made fresh every three days. After three days it will break down and no longer be effective.
If you miss a dose, give it as soon as you remember. If it is almost time for the next dose, skip the one you missed and go back to the regular schedule. Do not give 2 doses at once.
This medication should only be given to the pet for whom it was prescribed.

Possible Side Effects
Some animals may have vomiting and a slight worsening of the diarrhea at the beginning of treatment.
When using the injectable form of tylosin, pain and a local reaction at the injection site may occur.
Consult your veterinarian if you notice any of the above side effects.
If your pet experiences an allergic reaction to the medication, signs may include facial swelling, hives, scratching, sudden onset of diarrhea, vomiting, shock, seizures, pale gums, cold limbs, or coma. If you observe any of these signs, contact your veterinarian immediately.

Precautions
Not for use in animals hypersensitive (allergic) to tylosin, erythromycin, or other antibiotics in the macrolide class.
The safety of tylosin in pregnant or lactating animals (female animals nursing their young) is not known.
Do not use in horses.
Consult with your veterinarian regarding the physical examinations and laboratory testing necessary prior to and during treatment with tylosin.

Drug, Food, and Test Interactions
Consult your veterinarian before using tylosin with other medications, including vitamins and supplements, digoxin, methylprednisolone, warfarin, or theophylline, since interactions may occur.
It is generally recommended to not use tylosin with certain other antibiotics including lincomycin, chloramphenicol, and clindamycin.

Signs of Toxicity/Overdose
Toxicity is very rare. If you know or suspect your pet has had an overdose, contact your veterinarian immediately. 
Keep this and all other medications out of the reach of children and pets.

This information may not cover all possible uses, directions, side effects, precautions, allergic reactions, drug interactions, or withdrawal times.  Always consult your own veterinarian for specific advice concerning the treatment of your pet.