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Thyrovet by VetOne

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Thyrovet is manufacturer discontinued.  We recommend the product  Thyro-tab.

Generic Name:

Levothyroxine sodium

General Description:

Levothyroxine is an oral thyroid hormone medication used in dogs and cats to treat hypothyroidism or other thyroid conditions due to low circulating thyroid hormone. It usually needs to be given for the life of the animal. Levothyroxine is available as chewable tablets, as an oral solution, as a powder or as tablets.

What is this drug?
  • Levothyroxine is a synthetic thyroid hormone
  • Levothyroxine is given by mouth
Reasons for prescribing:
  • To treat conditions associated with low circulating thyroid hormone (hypothyroidism). This is a common disease of middle aged and older pets (where the animal's thyroid gland does not produce enough thyroid hormone)
  • Cats don't often receive levothryoxine, but may be prescribed it for a short period to correct overtreatment of hyperthyroidism or if their thyroid gland was surgically removed
What dogs/cats should not take this medication?
  • Hyperthyroid animals (pets which produce too much thyroid hormone)
  • Use with extreme caution in older or debilitated animals, those with heart disease, high blood pressure, anemia, Addison's disease (hypoadrenocorticism), or diabetes
  • Pets who have ever had thyrotoxicosis or have an uncontrolled adrenal problem
  • Pregnant or nursing animals
  • Pets known to have had an allergic reaction to levothyroxine or like products

Check with your veterinarian if this product can be given with or without food.

Give medication as directed by your veterinarian. This medication is usually given once or twice daily .

Read and follow the label carefully.

There are many different brands of thyroid replacement therapy. Differences do exist between brands. If you must change brands, your veterinarian may need to recheck thyroid hormone levels and adjust dosing accordingly.

Give the exact amount prescribed and only as often as directed. Missed doses reduce the effectiveness of therapy.

Ideally, give the medication at the same time daily.

Give any vitamin or mineral supplements an hour before or 4 hours after giving levothyroxine.

It usually needs to be given for the life of the animal.

Ensure your pet has fresh, clean drinking water at all times.

What if dose is missed?

If a dose is missed, give it as soon as you can. If it is time already for the next dose, skip the missed dose and go back to the normal schedule. Do not give two doses at the same time.

What to tell/ask veterinarian before giving medication?

Talk to your veterinarian about:

  • Thyroid hormone levels will need to be monitored with blood tests every few weeks until the dose is stabilized. Blood should be drawn 6-8 hours after the morning dose of medication. Schedule your appointment accordingly. Your veterinarian may also advise periodic liver and kidney function testing.
  • Risks and benefits of using this drug

Tell your veterinarian about:

  • If your pet has experienced side-effects on other drugs/products
  • If your pet has experienced digestive upset now or ever
  • If your pet has experienced liver or kidney disease now or ever
  • If your pet has experienced any other medical problems or allergies now or ever
  • All medicines and supplements that you are giving your pet or plan to give your pet, including those you can get without a prescription. Your veterinarian may want to check that all of your pet's medicines can be given together.
  • If your pet is pregnant or nursing or if you plan to breed your pet
Storage and Warnings:

Store in a tight, light resistant, childproof container in a cool, dry place at room temperature away from heat and direct sunlight.

Refrigerate oral solution if instructed.

Keep this and all medication out of reach of children and pets. Call your physician immediately if you accidentally take this product.

Potential side effects:
  • This medication is usually well tolerated by dogs and cats when given at the correct dose
  • Contact your veterinarian if your pet experiences any of these symptoms: fast heart rate, excessive ingestion of food, inability to tolerate heat, excitability, nervousness, excessive panting.
  • Long term use may cause osteoporosis (bone loss)
  • If you notice anything unusual, contact your veterinarian
Can this drug be given with other drugs?
  • Yes, but possible interactions may occur with antidepressants, digoxin, epinephrine, estrogens, insulin, ketamine, norepinephrine and warfarin
  • If you give your pet sucralfate (Carafate) or aluminum antacids (Maalox, Mylanta), give these products 4 hours before or after giving levothyroxine
  • If your pet experiences any unusual reactions when taking multiple medications, contact your veterinarian

Contact your veterinarian immediately if pet consumes more than the prescribed amount.

What else should I know?

Notify your veterinarian if your animal's condition does not improve or worsens despite this treatment.

As with all prescribed medicines, levothyroxine should only be given to the dog/cat for which it was prescribed. It should be given only for the condition for which it was prescribed. It is important to periodically discuss your pet's response to levothyroxine at regular check ups. Your veterinarian will best determine if your pet is responding as expected and if your pet should continue receiving levothyroxine.

This is just a summary of information about levothyroxine. If you have any questions or concerns about levothyroxine or for the condition it was prescribed, contact your veterinarian.

Soloxine, Thyrozine, Thyro­Tabs, Synthroid, Leventa, Nutrived T4 Chewable, Levocrine)

Common Drug Name
Levothyroxine (L­Thyroxine)

Common Brand Names
Soloxine, Thyrozine, Thyro­Tabs, Leventa, Nutrived T4 Chewable, Levocrine (veterinary forms)
Synthroid (human form)

Tablets: Store at room temperature in a tight, light resistant, childproof container. Liquid: Before first use, the oral solution should be stored refrigerated at 37°­46°F (2°­8°C) and protected from light. After first opening, store at room temperature 68°­77°F (20°­25°C) and use within 2 months.

Levothyroxine is a synthetic thyroid hormone. It usually needs to be given for the life of the animal when the animal is not producing enough thyroid hormone.
Dogs and Cats: Levothyroxine is used for the treatment of hypothyroidism, a condition in which the body does not produce enough thyroid hormone.
Birds: Levothyroxine is used for the treatment of respiratory clicking, vomiting, obesity, and thyroid responsive diseases.
Turtles: It is used for the treatment of hypothyroidism and to stimulate eating in debilitated turtles.

Dose and Administration
Always follow the dosage instructions provided by your veterinarian. If you have difficulty giving the medication, contact your veterinarian.
Dogs and Cats: Give by mouth. If approved by your veterinarian, it may be given with food.
Birds: Levothyroxine is usually administered in the drinking water.
Your veterinarian may monitor thyroid hormone levels in the blood every 2­4 weeks while adjusting the dose.
If you miss a dose, give it as soon as you remember. If it is almost time for the next dose, skip the one you missed and go back to the regular schedule. Do not give 2 doses at once.
This medication should only be given to the pet for whom it was prescribed.

Possible Side Effects
None if given at correct dosage.
Some species of red­feathered birds may start growing yellow feathers.
If your pet experiences an allergic reaction to the medication, signs may include facial swelling, hives, scratching, sudden onset of diarrhea, vomiting, shock, seizures, pale gums, cold limbs, or coma. If you observe any of these signs, contact your veterinarian immediately.

Differences exist between brands. Do not change brands if possible. If there is a need to change, your veterinarian may need to recheck thyroid hormone levels and adjust dose if indicated.
Not for use in animals hypersensitive (allergic) to it.
Use with extreme caution in older or debilitated animals, or those with heart disease, high blood pressure, Addison's disease (hypoadrenocorticism), or diabetes.
Do not use in animals with hyperthy­roidism, a condition in which the body produces too much thyroid hormone. The safety of this medication in pregnant and lactating animals (female animals nursing their young) has not been determined.
Consult with your veterinarian regarding the physical examinations and laboratory testing necessary prior to and during treatment with levothyroxine.

Drug, Food, and Test Interactions
Consult with your veterinarian before using levothyroxine with any other medications, including vitamins and supplements, epinephrine, norepinephrine, insulin, estrogens, warfarin, or digoxin, since interactions may occur.
No known food interactions.
Levothyroxine can alter the results of many laboratory tests. Tell your veterinarian your pet is on levothyroxine before any tests are performed.

Signs of Toxicity/Overdose
With chronic overdosing (taking a slightly higher dose over a long period of time), expect to see signs of hyperthyroidism such as an increase in drinking, urinating, eating, activity; seeking cool areas; increased heart rate; panting; restlessness; and behavior changes. May also see vomiting.
If you know or suspect your pet has had an overdose, or if you observe any of these signs in your pet, contact your veterinarian immediately.
Keep this and all other medications out of the reach of children and pets.

This information may not cover all possible uses, directions, side effects, precautions, allergic reactions, drug interactions, or withdrawal times. Always consult your own veterinarian for specific advice concerning the treatment of your pet.


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