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Benazepril HCI Tabs

Benazepril HCI Tabs by Amneal Pharmaceuticals

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Benazepril hydrochloride

Trade Names:

Fortekor® Flavor Tabs® (5 mg)
Lotensin®

General Description:

Benazepril is an ACE inhibitor used to dilate blood vessels in the treatment of high blood pressure, congestive heart failure and some types of kidney disease in dogs and cats.

What is this drug?
  • An angiotensin converting enzyme (ACE) inhibitor; a vasodilator and antihypertension agent
  • Dilates the veins and decreases fluid retention
  • Given by mouth
Reasons for prescribing:
  • To treat high blood pressure in dogs and cats
  • To treat congestive heart failure in dogs and cats
  • To treat some kidney conditions in dogs and cats
What dogs/cats should not take this medication?
  • This drug will not work well in pets with severe liver disease
  • Pets with lupus, blood abnormalities, a history of cardiac output failure or those with low sodium levels
  • Use with caution in cats weighing less than 2.5 kg
  • Pregnant or nursing pets
  • If your pet has had an allergic reaction to benazepril or other ACE inhibitors
Directions:

Read and follow the label carefully.

Give the exact amount prescribed and only as often as directed. It is usually given once daily and is usually given for the rest of the animal's life.

Benazepril may be given with or without food.

Give this medication for as long as veterinarian directs. Do not skip doses or stop giving the medication without consulting your veterinarian.

Heart failure patients: When benazepril is used along with a diuretic, blood work to assess kidney function should be measured prior to benazepril use, again 3-7 days later, and then periodically. Kidney function should also be rechecked after any dose change.

Call ahead for refills.

Ideally, give the medication at the same time(s) daily.

What if a dose is missed?

If a dose is missed, give it as soon as you can. If it is time already for the next dose, skip the missed dose and go back to the normal schedule. Do not give two doses at the same time.

What to tell/ask veterinarian before giving medication?

Talk to your veterinarian about:

  • When will your pet need to be rechecked
  • What tests may need to be performed prior to and during treatment with this drug
  • What are the risks and benefits of using this drug

Tell your veterinarian about:

  • If your pet has experienced side-effects on other drugs/products
  • If your pet has experienced digestive upset now or ever
  • If your pet has experienced liver or kidney disease now or ever
  • If your pet has experienced any other medical problems or allergies now or ever
  • All medicines and supplements that you are giving your pet or plan to give your pet, including those you can get without a prescription. Your veterinarian may want to check that all of your pet's medicines can be given together.
  • If your pet is pregnant or nursing or if you plan to breed your pet
Storage and Warnings:

Store in a tight, light resistant, childproof container in a cool, dry place at room temperature away from heat and direct sunlight.

Keep this and all medication out of reach of children and pets.

Call your physician immediately if you accidentally take this product.

Potential side effects:
  • Nausea, appetite loss, vomiting and diarrhea
  • Kidney dysfunction, which may cause increased thirst, changes in urination
  • Abnormally high potassium levels, which may cause weakness, slow heart rate and weak pulse
  • High doses can lead to very low blood pressure, which may cause weakness and collapse
  • If you notice any of these symptoms or if your pet's condition worsens contact your veterinarian
Can this drug be given with other drugs?
  • Yes, but possible interactions may occur with NSAIDS (ex. aspirin, meloxicam), potassium, potassium-sparing diuretics (ex. furosemide, spironolactone) and other vasodilators
  • If your pet experiences any unusual reactions when taking multiple medications, contact your veterinarian.
Overdosing?

Contact your veterinarian immediately if pet receives more than the prescribed amount.

What else should I know?

Notify your veterinarian if your animal's condition does not improve or worsens despite this treatment.

As with all prescribed medicines, benazepril should only be given to the pet for which it was prescribed. It should be given only for the condition for which it was prescribed.

This is just a summary of information about benazepril. If you have any questions or concerns about benazepril or the condition it was prescribed for, contact your veterinarian.

Benazepril
(Lotensin)

Generic Name
Benazepril

Common Brand Names
Lotensin
No generic products are available.

Storage
Refrigerate oral suspension. Store other forms at room temperature in a tight, light resistant, childproof container, protected from moisture. Do not store in the bathroom.

Uses
Benazepril is in a class of drugs called ACE inhibitors. It dilates the veins and decreases fluid retention. It is used to treat heart failure, high blood pressure, and some forms of kidney disease in dogs  and cats.

Dose and Administration
Always follow the dosage instructions provided by your veterinarian. If you have difficulty giving the medication, contact your veterinarian.
Give by mouth, with or without food.
Do not abruptly start or stop this medication without approval by your veterinarian.
Treatment is normally continued for the duration of the animal's life.
If you miss a dose, give it as soon as you remember. If it is almost time for the next dose, skip the one you missed and go back to the regular schedule. Do not give 2 doses at once.
This medication should only be given to the pet for whom it was prescribed.

Possible Side Effects
Side effects are uncommon but may include lack of appetite, vomiting, and diarrhea. Potentially could cause low blood pressure, which may cause weakness or collapse; kidney dysfunction, which may cause increased thirst and/or changes in urination; and abnormally high potassium levels, which may cause weakness, a slow heart rate, and a weak pulse. Consult your veterinarian if you notice any of the above side effects or if your pet’s condition worsens.
Abnormalities of the blood and skin rashes have rarely occurred in humans. These have not been seen in animals.
If your pet experiences an allergic reaction to the medication, signs may include facial swelling, hives, scratching, sudden onset of diarrhea, vomiting, shock, seizures, pale gums, cold limbs, or coma. If you observe any of these signs, contact your veterinarian immediately.

Precautions
Not for use in animals hypersensitive (allergic) to this drug or other ACE inhibitors.
Use with caution in animals with very low blood sodium levels. 
Not for use in animals with lupus or blood abnormalities.
Not for use in pregnant animals. May be used in lactating animals (female animals nursing their young).
Animals with liver disease may not be able to properly convert the medication to its active form.
Consult your veterinarian regarding the physical examinations and laboratory testing needed prior to and during treatment with benazepril.

Drug and Food Interactions
Consult your veterinarian before using benazepril with any other medications, including vitamins and supplements, diuretics (e.g. Lasix, Salix), other vaso­dilators, non-steroidal anti-inflammatory drugs (NSAIDs) e.g., aspirin, etodolac (EtoGesic), carprofen (Novox or Rimadyl), meloxicam (Metacam, firocoxib (Previcox), tepoxalin (Zubrin), or deracoxib (Deramaxx), since interactions may occur.
 High potassium levels may develop if potassium supplements, or potassium-sparing diuretics, are given at the same time as benazepril.

Signs of Toxicity/Overdose
The most common sign of an overdose is weakness or collapse. 
If you know or suspect your pet has had an overdose, or if you observe any of these signs in your pet, contact your veterinarian immediately.
Keep this and all other medications out of the reach of children and pets.

This information may not cover all possible uses, directions, side effects, precautions, allergic reactions, drug interactions, or withdrawal times.  Always consult your own veterinarian for specific advice concerning the treatment of your pet.


 
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