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Pilocarpine

Pilocarpine by Akorn

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Pilocarpine hydrochloride ophthalmic

Trade Names:
Pilocar®
Pilopine-HS®

General Description:

This drug is an eye medication that is used in dogs and cats to decrease the pressure in the eye. It is available in the form of drops.

What is this drug?
• A cholinergic agent

Reasons for prescribing:
• To treat primary glaucoma

What dogs/cats should not take this medication?
• Animals with secondary glaucoma
• Animals that may be pregnant or nursing
• Animals with a known hypersensitivity or allergy to this drug should not take this medication

Directions:

Read and follow the prescription label carefully.

Give the exact amount prescribed and only as often as directed.

Give this medication for as long as your veterinarian directs.

Do not skip doses or stop giving the medication without consulting your veterinarian.

Glaucoma requires long-term eye medications and frequent monitoring of intraocular pressures.

Dose adjustments will be made based upon these results and an assessment of how your dog or cat is responding clinically.

If your pet requires more than one medication in the same eye, administer the medications 5 minutes apart.

If your pet requires more than one medication, discuss with your veterinarian if it is preferable to administer drops before ointments.

If you are having difficulty applying the medication, contact your veterinarian.

Call ahead for refills.

Ideally, give this medication at the same time(s) daily.

Administration of eye drops
• Wash your hands before applying any eye medication
• Check label directions and shake bottle if necessary
• Remove excess discharge from around the eye with a moistened cloth
• Remove the cap and avoid contaminating the tip of the medication bottle with the environment or your fingers
• Tilt your pet's head back so that they are looking up towards the ceiling
• Gently hold the eyelids open and with the other hand holding the medication bottle, rest your hand above the eye
• Be sure that the tip of the medication bottle is not pointed towards the eye in case of any sudden movements
• Ensure that the tip of the medication bottle does not touch your pet's eye, eyelids, or lashes
• Apply the correct amount of drops into the eye
• Continue to hold your pet's head up and allow them to blink to distribute the drops over the entire eye
• Place the cap back on the medication bottle and avoid contaminating the inside of the cap with your fingers
• Wash your hands after applying any eye medication
• Always praise and reward your pet to encourage cooperation

What if a dose is missed?

If a dose is missed, give it as soon as you can. If it is time already for the next dose, skip the missed dose and go back to the normal schedule. Do not give two doses at the same time.

What to tell/ask a veterinarian before giving medication?

Talk to your veterinarian about:
• When your pet will need to be rechecked
• What tests may need to be performed prior to and during treatment with this drug
• What are the risks and benefits of using this drug

Tell your veterinarian about:
• If your pet has experienced previous eye problems
• If your pet has experienced side-effects on other drugs/products
• If your pet has experienced digestive upset now or ever
• If your pet has experienced liver or kidney disease now or ever
• If your pet has experienced any other medical problems or allergies now or ever
• All medicines and supplements that you are giving your pet or plan to give your pet, including those you can get without a prescription. Your veterinarian may want to check that all of your pet's medications can be given together.
• If your pet is pregnant, nursing or if you plan to breed your pet

Storage and Warnings:

Pilocarpine hydrochloride ophthalmic should be stored in a childproof container in a cool, dry place at room temperature away from heat and direct sunlight.

Do not use any eye drops that have become discolored or have particles in them.

Keep this and all medication out of reach of children and pets.

Call your physician immediately if you accidentally take this product.

Potential side effects:
• This medication may cause the eye to sting for a short period after application
• This medication can cause local irritation resulting in redness of the tissues surrounding the eye
• This medication can cause excess salivation, vomiting and diarrhea
• If these symptoms persist or you notice anything else unusual, contact your veterinarian

Can this drug be given with other drugs?
• Do not give new food or medications without first talking to your veterinarian
• If your pet experiences any unusual reactions when taking multiple medications, contact your veterinarian

Overdosing?

Contact your veterinarian immediately if you pet has accidentally ingested this medication or has received more than the prescribed amount.

What else should I know?

Notify your veterinarian if your animal's condition does not improve or worsens despite this treatment.

As with all prescribed medicines, Pilocarpine hydrochloride ophthalmic should only be given to the pet for which it was prescribed.

It should be given only for the condition for which it was prescribed. Never use skin or ear medications in the eye.

This is just a summary of information about Pilocarpine hydrochloride ophthalmic. If you have any questions or concerns about Pilocarpine hydrochloride ophthalmic or the condition it was prescribed for, please contact your veterinarian.

Nystatin/Neomycin/Thiostrepton/Triamcinolone
(Animax, Panolog)

Common Drug Name
Nystatin, neomycin, thiostrepton, triamcinolone

Common Brand Names
Panolog, Animax

Storage
Store at room temperature.

Uses
Nystatin is an antifungal, effective against many types of yeast. Neomycin and thiostrepton are antibiotics. Triamcinolone is a corticosteroid. The combination is used to treat skin and ear disorders caused by allergies, or bacterial or yeast infections. It is also used for infections of the anal gland and interdigital (between the toes) cysts.

Dose and Administration
Always follow the dosage instructions provided by your veterinarian. If you have difficulty applying the medication, contact your veterinarian.
The ear or area of skin should be thoroughly cleaned and dried before treatment. For the ear, remove any debris, crusty material, etc., with a suitable non­irritating ear cleaning solution. For the skin, use a skin cleansing solution to clean the lesion and adjacent area. Clip any excessive hair from the ear or treatment area as directed by your veterinarian.
If you miss a dose, apply it as soon as you remember. If it is almost time for the next dose, skip the application you missed and go back to the regular schedule.  Do not apply 2 doses at once.
This medication should only be given to the pet for whom it was prescribed.

Possible Side Effects
In rare instances, an animal may be sensitive to neomycin, causing redness in the area the medication was applied. If so, contact your veterinarian.
When used in the ear, may see loss of hearing or balance if the eardrum is not intact. If you see these signs, contact your veterinarian. 
If ingested, or given at high doses or for prolonged periods of time, side effects related to the triamcinolone may be seen. The most common effect is an increase in the amount of drinking and urinating. Less commonly you may see an increased appetite and weight gain, panting, diarrhea, vomiting, and behavior changes. 
Contact your veterinarian if side effects are noticed or if the condition worsens.
If your pet experiences an allergic reaction to the medication, signs may include facial swelling, hives, scratching, sudden onset of diarrhea, vomiting, shock, seizures, pale gums, cold limbs, or coma. If you observe any of these signs, contact your veterinarian immediately.

Precautions
Not for use in animals hypersensitive (allergic) to any of the ingredients.
Avoid contact with the eyes.
Not for use in deep infections, puncture wounds, burns, or if pus is present.
Prevent ingestion of the medication. If ingested at high doses or for extended periods, corticosteroids can cause premature birth especially toward the end of pregnancy. In dogs, rabbits, and rodents, corticosteroids can cause birth defects.
A veterinary exam of the ear is necessary prior to use of this product. It should not be used in animals with a perforated eardrum.
Corticosteroids, if given at high doses or for extended periods, can cause delayed wound healing and immunosuppression resulting in an increased risk of bacterial or fungal infections.

Drug, Food, and Test Interactions
Consult your veterinarian before using this medication with any other medications, including vitamins and supplements, corticosteroids, or gentamicin, since interactions may occur. 
If ingested, there is an increased risk of stomach ulcers when corticosteroids are used with non-steroidal anti-inflammatory drugs (NSAIDs) such as aspirin, carprofen (Rimadyl), deracoxib (Deramaxx), or etodolac (EtoGesic).

Signs of Toxicity/Overdose
Adverse reactions and toxicities are unlikely if used according to directions. 
If you know or suspect your pet has ingested this medication, or observe any unusual signs, symptoms, or behaviors in your pet, contact your veterinarian immediately.
Keep this and all other medications out of the reach of children and pets.

This information may not cover all possible uses, directions, side effects, precautions, allergic reactions, drug interactions, or withdrawal times.   Always consult your own veterinarian for specific advice concerning the treatment of your pet.


 

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