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Urocit-K by Mission Pharmaceuticals

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Urocit-K 5mEq (540 mg) 100 Tablet Bottle

Potassium citrate is used as an aid in the prevention of urinary stone formation by increasing urinary pH.Potassium citrate is a prescription medication available as controlled release tablets and granules.

Side effects:
Side effects of potassium citrate include the development of hyperkalemia with symptoms such as muscle weakness, vomiting, diarrhea and heart arrhythmias.

Do not use in animals with hyperkalemia, kidney failure, Addison’s disease or dehydration. Use with caution when given with ACE inhibitors such as enalapril, diuretics such as furosemide, NSAIDs such as carprophen or aspirin.

Potassium citrate is FDA approved for use in dogs and cats. The dose varies with the product used and the disease being treated. Consult your veterinarian. This medication should be given with food.

Potassium citrate supplement

Common Brand Names

NutriVed™ Potassium Citrate Granules for Cats and Dogs
Potassium Citrate Granules
Resvive™ for Dogs
V.E.T. Pharmaceuticals K-Cit-V™


Potassium Citrate Supplements should be stored in a childproof container in a cool, dry place at room temperature away from heat and direct sunlight.

Bladder stones are a common occurrence in dogs and cats.  Several factors are involved in their development including diet, change in urine pH, and formation of crystals.  Encouraging a less acidic urine or urine with a higher pH can help reduce or prevent the risk of certain bladder stones forming. Urinary tract infections are also commonly associated with bladder stones.
Potassium Citrate is a supplement that promotes a less acidic urine or urine with a higher pH and reduces the risk of calcium oxalate bladder stone formation
This product is given by mouth and is commonly available as chewable tablets and/or granules

Reasons for using this product:
  • Commonly used to help prevent or reduce the risk of calcium oxalate bladder stones
What dogs/cats should not take this product?
  • Should not be used in animals with a history of struvite crystals or bladder stones
  • Should not be used in animals with high blood levels of potassium such as with adrenal disease, kidney disease, or untreated diabetes mellitus
  • Should not be used in animals with severe heart or kidney disease
  • This supplement is not a replacement for appropriate antibiotic treatment when an active urinary tract infection is present
  • Safety in breeding, pregnant, or nursing animals has not been established
  • Animals with a known hypersensitivity or allergy to this supplement should not take this product
Dose and Administration
Potassium Citrate Supplements should be given according to your veterinarian’s instructions. Read and follow the product label carefully.

It is ideal to give this supplement at the same time daily.  This supplement should be given with food to avoid digestive upset.  The formulation is commonly applied on top of the food. Ensure that your pet eats the full meal to receive the appropriate dose. 

Animals prone to bladder stones and urinary tract infections are frequently monitored with urine examinations or urinalysis.  If your pet is receiving this supplement, your veterinarian will want to monitor their urine.

Supplements are not regulated by the FDA.  As such, they have not been required to go through the same rigorous testing for efficacy that drugs undergo.  Many products on the market are high quality and are made by reputable companies.  Consult with your veterinarian to choose the right product for your pet.

If a dose is missed, give it as soon as you can. If it is time already for the next dose, skip the missed dose and go back to the normal schedule. Do not give two doses at the same time.

Possible Side Effects

These products are usually well tolerated and adverse reactions are uncommon at recommended doses.
Could affect the gastrointestinal system causing inappetence, vomiting, or diarrhea
Notify your veterinarian immediately if your pet experiences any adverse reactions to this product
Keep this and all medication out of reach of children and pets.
Call your physician immediately if you accidentally take this product.As with all supplements, it should only be given to the pet for which it was recommended
Drug, Food and Test Interactions
  • Commonly used in combination with antibiotics when treating active urinary tract infections.
  • Caution is advised when using with ACE inhibitors (benazepril and enalapril), antacids, aspirin, digoxin, fluoroquinolones (ciprofloxacin and enrofloxacin), heparin, NSAIDS, and spironolactone.
  • Drugs not listed may also interact with Potassium Citrate Supplements.
  • Do not give new food or medications without first talking to your veterinarian.
  • If your pet experiences any unusual reactions when taking multiple medications, contact your veterinarian.
Signs of Toxicity/Overdose
Contact your veterinarian immediately if your pet receives more than the recommended amount.

This information may not cover all possible uses, directions, side effects, precautions, allergic reactions, drug interactions, or withdrawal times.  Always consult your own veterinarian for specific advice concerning the treatment of your pet. 


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